The Wolter Lab studies how genetic variation – common and rare – affects risk and resilience to neurodevelopmental disorders

We use genetic, molecular, cellular, and bioinformatics techniques to understand causal disease mechanisms, and, along the way, learn about how the brain develops. We employ a range of experimental systems, from genetically diverse human cell lines, mouse models, and human clinical data.

Members of the Lab come from diverse backgrounds and interests. We train graduate students from the Genetics, Neuroscience, and Cell and Molecular Biology training programs, with affiliations with the Waisman  Center, Stem Cell & Regenerative Medicine Center, and the Center for Genomic Science Innovation. In all, we are interested in questions across multiple scales, from DNA and RNA sequence, to cellular and tissue development, to the level of the whole organism.

We are always looking for passionate, curious thinkers who are interested in neurogenetics or brain development. Please contact us if you are interested in learning more about what we do, or want to join the lab!

News

  • Wisconsin Partnership Program New Investigator Program

    Many thanks to the WPP for their support and guidance of our project on leveraging iPSC libraries for well-powered human genetic studies.  This collaborative project will make use of lines from the WiCell Stem Cell …

  • Eagles Autism Challenge!

    Many thanks to the Eagles Autism Challenge for supporting our project to identify common genetic modifiers in autism!

  • Sabrina and Aayushi join the team!

    Big big welcome to Aayushi and Sabrina as the first PhD students in the lab. It takes bravery to be the first anything, and we are fortunate to have two passionate thinkers join the team!

  • 2023 Rotators

    We had a great group of grad students rotate through the lab this year.  Many thanks to Sabrina, Brooke, Aayushi, Rachel, Uma, Sam, and Amber for your hard work!

  • Wolter Lab Attends SFN2023!

    Congrats to Sam for presenting her work on RNA trafficking in ARSACS neurons and Edison for attending his first conference!!! Wild talks included RNA trafficking and local synaptic translation, brain machine interfaces, and the organization …

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