The Wolter Lab studies how genetic variation – common and rare – affects risk and resilience to neurodevelopmental disorders
We use genetic, molecular, cellular, and bioinformatics techniques to understand causal disease mechanisms, and, along the way, learn about how the brain develops. We employ a range of experimental systems, from genetically diverse human cell lines, mouse models, and human clinical data.
Members of the Lab come from diverse backgrounds and interests. We train graduate students from the Genetics, Neuroscience, and Cell and Molecular Biology training programs, with affiliations with the Waisman Center, Stem Cell & Regenerative Medicine Center, and the Center for Genomic Science Innovation. In all, we are interested in questions across multiple scales, from DNA and RNA sequence, to cellular and tissue development, to the level of the whole organism.
We are always looking for passionate, curious thinkers who are interested in neurogenetics or brain development. Please contact us if you are interested in learning more about what we do, or want to join the lab!
News
Two new papers out this week
Two new papers were published this week by each of Justin’s post-doc labs! The first paper, led by the trio of Nana Matoba, Bran Le, and Jordan Valone of the Stein lab and published in …
The ARSACS Foundation Funds Anti-Inflammatory Drug Study
Many thanks to the ARSACS Foundation, who is supporting a project to test whether targeting neuroinflammation can slow ataxia progression in the mouse model of ARSACS. This project will be led by Dr. Wang, who …
Dr. Huaxia Wang joins the lab!
A big welcome to Dr. Huaxia Wang, who brings considerable expertise on molecular chaperones and protein interactions in the context of neurodegeneration.
Wolter lab welcomes Marc and Alan!
A big big welcome to our first undergraduate researchers! Ziyi (Alan) Liu is a rising senior in the Biology program, and is soaking up all the techniques he can before his research project starts in …
Dr. Chris Bolden of XULA visits the lab
Chris Bolden, an Assistant Professor from Xavier University of Louisiana, spent two weeks in the lab sharing his expertise on cellular models of the blood brain barrier, and learning up some iPSC techniques to take …
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